| Registro completo |
| Provedor de dados: |
BJM
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| País: |
Brazil
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| Título: |
Antimicrobial susceptibility of Streptococcus pneumoniae and genotypic characterization of erythromycin-resistant strains in Porto Alegre, Brazil
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| Autores: |
Weber,F. T.
Dias,C.
Costa,M. da
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| Data: |
2010-03-01
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| Ano: |
2010
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| Palavras-chave: |
Streptococcus pneumoniae
Drug resistance
Erm(B)
Mef(A/E)
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| Resumo: |
The antimicrobial susceptibility of 64 strains of S. pneumoniae obtained from three hospitals in Porto Alegre, Brazil, isolated between 2004 and 2005, was determined, using the agar-dilution method. The prevalence of resistant (intermediate and full resistance) strains to trimethoprim/sulphamethoxazole, penicillin, tetracycline, erythromycin, chloramphenicol, and ceftriaxone were 68%, 28%, 18%, 15%, 3%, and 1%, respectively. All strains were susceptible to vancomycin. Among 18 penicillin-resistant strains, 7 were resistant to at least two other antimicrobial drugs. All erythromycin-resistant strains, except one, contained the erm(B) and/or mef(A/E) genes, with a predominance of the former. The resistance rate to penicillin and erythromycin in Porto Alegre remained stable. The combination of trimethoprim/ sulphamethoxazole should not be recommended to treat pneumococcal infections, because of the high rate of resistant strains.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000100001
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| Editor: |
Sociedade Brasileira de Microbiologia
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| Relação: |
10.1590/S1517-83822010000100001
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Microbiology v.41 n.1 2010
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| Direitos: |
info:eu-repo/semantics/openAccess
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